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\u6211\u76f8\u4fe1\u5982\u679c\u6709\u4e9b\u4ea7\u54c1\u88ab\u8bc1\u660e\u4e0d\u9002\u5408\u5e7f\u6cdb\u98df\u7528\uff0c\u6216\u8005\u6709\u79cd\u79cd\u7f3a\u70b9\uff0c\u90a3\u5c31\u8bc1\u660e\u8fd9\u662f\u4e00\u6761\u6b67\u8def\uff0c\u5927\u5bb6\u5e94\u8be5\u63a2\u5bfb\u522b\u7684\u65b9\u5411\uff0c\u7ee7\u7eed\u524d\u884c\u3002<\/span>\u56e0\u4e3a\u6280\u672f\u4e00\u5b9a\u8981\u8fed\u4ee3\uff0c\u79d1\u5b66\u4e00\u5b9a\u8981\u8fdb\u6b65\u3002<\/span>\u79d1\u5b66\u7684\u610f<\/span>\u4e49\uff0c\u5c31\u662f\u8ba9\u4eba\u7c7b\u80fd\u6709\u5f97\u9009\uff0c\u80fd\u65e2\u8981\u53c8\u8981\u3002<\/span>\u5982\u679c\u518d\u8ba9\u6211\u91cd\u8fd4\u90a3\u4e9b\u7cd6\u4e0a\u763e\u7684\u65e5\u5b50\uff0c\u4ee5\u6211\u73b0\u5728\u7684\u72b6\u6001\uff0c\u6211\u95f9\u4e0d\u597d\u4f1a\u6b7b\u3002<\/span>\u6240\u4ee5\u6211\u8fd8\u662f\u4e00\u4e2a\u7ed3\u8bba\uff0c\u4ee3\u7cd6\u4e0d\u5b8c\u7f8e\uff0c\u4f46\u7cd6\u662f\u771f\u64cd\u6de1\u3002<\/span><\/section>\n
\u4e00\u4e2a\u7ed3\u6784\u5f0f\u4e0a\u4e00\u4e2a\u4f4d\u70b9\u662f\u7ed9\u7535\u5b50\u7684\u7532\u57fa\u4e59\u57fa\u8fd8\u662f\u7532\u6c27\u57fa\u3001\u8fd8\u662f\u5438\u7535\u5b50\u7684\u785d\u57fa\uff0c\u662f\u5de6\u65cb\u8fd8\u662f\u53f3\u65cb\uff0c\u7406\u5316\u6027\u8d28\u90fd\u6709\u53ef\u80fd\u5929\u5dee\u5730\u522b\u3002<\/span><\/section>\n
\u67d0\u79cd\u4ee3\u7cd6\u5230\u5e95\u6709\u6ca1\u6709\u5b89\u5168\u98ce\u9669\uff0c\u9700\u8981\u5bf9\u5b83\u7684\u67d0\u4e00\u7279\u5b9a\u7ed3\u6784\u5f0f\u8fdb\u884c\u957f\u671f\u63a7\u5236\u53d8\u91cf\uff0c\u8fdb\u884c\u9488\u5bf9\u6027\u7814\u7a76\u3002<\/span><\/section>\n
\u4e00\u4e2a\u4e0d\u5b89\u5168\u5c31\u5426\u5b9a\u4e86\u6574\u4e2a\u9886\u57df\uff0c\u8fd9\u79cd\u5145\u6ee1\u8bef\u5bfc\u6027\u53c8\u65e0\u79d1\u5b66\u4f9d\u636e\u7684\u53d1\u8a00\u3002<\/span><\/section>\n
\u8fd9\u79cd\u884c\u4e3a\u6211\u613f\u79f0\u4e4b\u4e3a\u56e0\u564e\u5e9f\u98df\uff0c\u524a\u8db3\u9002\u5c65\uff0c\u5b69\u5b50\u548c\u6d17\u6fa1\u6c34\u4e00\u5757\u6cfc\uff0c\u4fbf\u79d8\u5c31\u7528\u7535\u952f\u5f00\u773c\u3002<\/span><\/section>\n

\u9752\u9709\u7d20\u8bde\u751f\u4e86\uff0c\u672a\u6765\u6216\u8bb8\u4f1a\u6709\u4eba\u4ea7\u751f\u6297\u751f\u7d20\u8010\u836f\u6027\u7684\u95ee\u9898\uff0c\u4f46\u8fd9\u662f\u4eba\u6ee5\u7528\u5de5\u5177\u7684\u95ee\u9898\uff0c\u800c\u4e0d\u662f\u7f6a\u5728\u5de5\u5177\u672c\u8eab\uff0c\u5e76\u4e0d\u610f\u5473\u7740\u4eba\u7c7b\u5c31\u5e94\u8be5\u91cd\u65b0\u9760\u514d\u75ab\u529b\u8ddf\u75c5\u83cc\u4f60\u6b7b\u6211\u6d3b\u3002<\/span>\u4ee3\u7cd6\u4e5f\u4e00\u6837\uff0c\u662f\u4e2a\u5ea6\u7684\u95ee\u9898\u3002<\/span><\/p>\n

02<\/span><\/strong><\/p>\n

\u90a3\u987a\u7740\u201c\u4ee3\u7cd6\u4e0d\u5b89\u5168\u201d\u8fd9\u4e2a\u8bba\u70b9\uff0c\u968f\u540e\u5f80\u524d\u7ffb\u8bb8\u591a\u5a92\u4f53\u7684\u8bba\u636e\uff0c\u6211\u89c9\u5f97\u5f88\u8352\u8bde\u3002<\/span>\u5f88\u591a\u8bba\u636e\u662f\uff0c\u54ea\u4e9b\u54ea\u4e9b\u4e13\u5bb6\uff0c\u54ea\u4e2a\u54ea\u4e2a\u5927\u5b66\uff0c\u505a\u4e86\u4e2aXXX\u7684\u7814\u7a76\uff0c\u8bc1\u660e\u4e86\u4ee3\u7cd6\u662f\u6709XX\u98ce\u9669\u7684\u3002<\/span>\u8bb2\u5b9e\u8bdd\uff0c\u6211\u770b\u5230<\/span>\u8fd9\u79cd\u601d\u7ef4\u65b9\u5f0f\uff0c\u6211\u60f3\u7b11\u3002<\/span>\u8ba8\u8bba\u79d1\u5b66\u95ee\u9898\u65f6\uff0c\u4e0d\u7ed9\u5f15\u7528\u51fa\u5904\u7684\uff0c\u4e00\u5f8b\u6309\u653e\u5c41\u5904\u7406\u3002<\/span><\/p>\n<\/section>\n

\n
\u7ed9\u4e86\u5f15\u7528\u51fa\u5904\uff0c\u5374\u662f\u4e00\u4e2a\u7edf\u8ba1\u5b66\u5185\u5bb9\uff0c\u90a3\u5c31\u662f\u770b\u4e00\u4e50\uff0c\u6211\u53ef\u662f\u6b63\u513f\u516b\u7ecf\u5199\u8fc7\u7edf\u8ba1\u5b66\u7b11\u8bdd\u7684\u7537\u4eba\uff0c\u7edf\u8ba1\u5b66\u662f\u8fd9\u4e2a\u4e16\u754c\u4e0a\u6700\u80fd\u516c\u5f00\u9020\u5047\u7684\u5b66\u79d1\u4e4b\u4e00\u4e86\uff0c\u53ea\u8981\u4f60\u4e0d\u8981\u8138\uff0c\u53d6\u6570\u591f\u65e0\u803b\uff0c\u8861\u91cf\u6807\u51c6\u591f\u4e3b\u89c2\uff0c\u4ec0\u4e48\u7ed3\u8bba\u4f60\u90fd\u53ef\u4ee5\u5f97\u51fa\u6765\u3002<\/span><\/section>\n
\u5c31\u62ff\u5f88\u7ecf\u5178\u7684\u4ec0\u4e48\u4e00\u9879\u6cd5\u56fd\u5341\u4e07\u4eba\u7684\u7814\u7a76\u8bc1\u660e\u4ee3\u7cd6\u6216\u589e\u52a0\u60a3\u764c\u98ce\u9669\uff0c\u4ee5\u6b64\u5f97\u5230\u7ed3\u8bba\uff0c\u4ee3\u7cd6\u4e0d\u5b89\u5168\u3002<\/span><\/section>\n
\u6211\u5e2e\u627e\u4e0b\u539f\u6587\u3002<\/span><\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n
\n

\u8fd9\u5219\u79d1\u6280\u65e5\u62a5\u57282022\u5e743\u670830\u65e5\u7b2c004\u7248\u520a\u767b\u7684\u300a\u98df\u7528\u4ee3\u7cd6\u6216\u589e\u52a0\u60a3\u764c\u98ce\u9669\u300b\u8868\u793a\uff0c<\/span>\u7814\u7a76\u62ff\u5230\u4e86\u8fd9\u4e9b\u4eba\u7684\u6027\u522b\u3001\u5e74\u9f84\u3001\u6559\u80b2\u7a0b\u5ea6\u3001\u75c5\u53f2\u3001\u996e\u98df\u3001\u751f\u6d3b\u65b9\u5f0f\u3001\u5065\u5eb7\u6570\u636e\u7b49\u6570\u636e\uff0c\u5f97\u5230\u8fd9\u4e9b\u4eba\u4e2d\u67093358\u540d\u65b0\u53d1\u764c\u75c7\u75c5\u4f8b\uff0c\u8bca\u65ad\u65f6\u5e73\u5747\u53d1\u75c5\u5e74\u9f8459.5\u00b112.2\u5c81\uff0c\u8bc1\u660e\u4ee3\u7cd6\u6216\u589e\u52a0\u60a3\u764c\u98ce\u9669\u3002<\/p>\n

\u6211\u4e3a\u4ec0\u4e48\u8bf4\u770b\u4e00\u4e50\uff1f<\/span><\/section>\n
\u5927\u54e5\uff0c\u4e14\u4e0d\u8bf4\u5b83\u8fd9\u4e2a\u5b9e\u9a8c\u63a7\u5236\u6ca1\u63a7\u5236\u53d8\u91cf\uff0c\u8003\u8651\u522b\u7684\u56e0\u7d20\u3002<\/span><\/section>\n
\u4f60\u5c31\u770b\u8fd9\u4e2a\u5c0f\u516d\u5341\u5c81\u7684\u53d1\u75c5\u5e74\u9f84\uff0c\u5c31\u7b97\u662f\u5565\u4e5f\u4e0d\u559d\uff0c\u4ed6\u4e5f\u662f\u764c\u75c7\u9ad8\u53d1\u671f\uff0c\u4f60\u4e0d\u4fe1\u4f60\u53bb\u95ee\u4f60\u8eab\u8fb9\u5356\u4fdd\u9669\u7684\uff0c\u8fd9\u4e2a\u5e74\u9f84\u8fd8\u5356\u4e0d\u5356\u4ed6\u4eec\u91cd\u75be\u9669\uff1f<\/span><\/section>\n
\u8fd9\u4e2a\u5e74\u9f84\u662f\u80fd\u8ba9\u4fdd\u9669\u516c\u53f8\u6709\u4fdd\u8d39\u6536\u90fd\u4e0d\u613f\u610f\u62ff\u7684\u7fa4\u4f53\uff0c\u4f60\u731c\u731c\u770b\u4fdd\u9669\u516c\u53f8\u50bb\u8fd8\u662f\u4e0d\u50bb\uff1f<\/span><\/section>\n
\u5982\u679c\u7167\u8fd9\u4e2a\u7b97\u6cd5\uff0c\u5230\u4e86\u8fd9\u4e2a\u5e74\u9f84\u53d1\u75c5\uff0c\u4ed6\u4eec\u5bb6\u90bb\u5c45\u7684\u72d7\u4e0b\u5d3d\u5b50\u4e86\uff0c\u4e5f\u4f1a\u5bfc\u81f4\u4ed6\u764c\u75c7\u9ad8\u53d1\u3002<\/span><\/section>\n
\u4ed6\u5403\u5965\u5229\u7ed9\u4e5f\u5bfc\u81f4\u764c\u75c7\u9ad8\u53d1\u3002<\/span><\/section>\n
\u4ed6\u51cc\u6668\u4e09\u70b9\u5728\u5395\u6240\u91cc\u53d8\u540e\u7a7a\u7ffb\u53d8\u5403\u9e21\u86cb\u704c\u997c\uff0c\u4e5f\u4f1a\u5bfc\u81f4\u764c\u75c7\u9ad8\u53d1\u3002<\/span><\/section>\n
\u751a\u81f3\u6211\u518d\u7ed9\u5927\u5bb6\u4e3e\u4e2a\u4f8b\u5b50\u3002<\/span><\/section>\n
\u6bd4\u5982\u8bf4\u5927\u5bb6\u505a\u5bf9\u7167\u8bd5\u9a8c\uff0c\u4e00\u5343\u4e2a\u5929\u5929\u559d\u624b\u78e8\u5496\u5561\u7684\uff0c\u548c\u4e00\u5343\u4e0d\u559d\u5496\u5561\u7684\uff0c\u8ddf\u8e2a\u8c03\u7814\u540e\u53d1\u73b0\u524d\u8005\u66f4\u5065\u5eb7\u3002<\/span><\/section>\n
\u4f60\u80fd\u8bc1\u660e\u624b\u78e8\u5496\u5561\u6709\u5229\u4e8e\u8eab\u4f53\u5065\u5eb7\u5417\uff1f<\/span><\/section>\n
\u4e0d\u80fd\uff0c\u4f60\u6709\u6ca1\u6709\u8003\u8651\u8fc7\u524d\u8005\u53ef\u80fd\u6bd4\u540e\u8005\u66f4\u6709\u94b1\uff0c\u4ed6\u7269\u8d28\u6761\u4ef6\u5728\u8fd9\u91cc\uff0c\u4ed6\u652f\u6491\u7684\u8d77\u5929\u5929\u559d\u5496\u5561\uff0c\u4ed6\u5c31\u662f\u751f\u6d3b\u7684\u597d\uff0c\u6240\u4ee5\u5bb9\u6613\u6bd4\u540e\u8005\u66f4\u5065\u5eb7\uff1f<\/span><\/section>\n
\u8fd9\u4e0d\u5178\u578b\u7684\u5f52\u56e0\u8c2c\u8bef\u5417\uff1f\u00a0<\/span><\/section>\n
\u5f88\u660e\u663e\u8ba9\u4ed6\u5065\u5eb7\u7684\u4e0d\u662f\u5496\u5561\uff0c\u800c\u662f\u94b1\u3002<\/span><\/section>\n
\u6240\u4ee5\u771f\u7684\uff0c\u7edf\u8ba1\u5b66\u8fd9\u4e1c\u897f\u771f\u7684\u662f\u4efb\u4eba\u6253\u626e\u3002<\/span><\/section>\n
\u540c\u6837\u7684\u4fe1\u606f\u5dee\u95ee\u9898\uff0c\u5728\u6211\u7814\u7a76\u65f6\u53cd\u590d\u51fa\u73b0\uff0c\u6211\u53d1\u73b0\u8bb8\u591a\u5185\u5bb9\u6b63\u4e3b\u6ca1\u5b9a\u8bba\u7684\u8bba\u6587\uff0c\u5f88\u591a\u4eba\u76f4\u63a5\u5e2e\u79d1\u7814\u4eba\u5458\u7ed9\u4ee3\u7cd6\u5224\u4e86\u6b7b\u5211\u3002<\/span><\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n
\n
\u6bd4\u5982\u8fd9\u4e2a\u7ed3\u5c3e\u7684\u82f1\u6587\uff0c\u5927\u5bb6\u770b\u4e00\u4e0b\u3002\uff08To establish a causal link, replication in other large-scale prospective cohorts and mechanistic investigations are needed. \uff09<\/span><\/section>\n
\u8bba\u6587\u7684\u610f\u601d\u662f\uff0c\u53ef\u80fd\u4e0d\u5b89\u5168\uff0c\u9700\u8981\u5927\u89c4\u6a21\u7684\u8c03\u67e5\u7814\u7a76\u3002<\/span><\/section>\n
\u79d1\u7814\u627e\u5230\u201c\u53ef\u80fd\u201d\u4e0d\u96be\uff0c\u4e00\u9524\u5b9a\u97f3\uff0c\u8bc1\u660e\u201c\u80fd\u201d\uff0c\u5f88\u96be\uff0c\u56e0\u4e3a\u79d1\u7814\u662f\u5f88\u4e25\u8c28\u3002<\/span><\/section>\n
\u4ee3\u7cd6\u4e0d\u662f\u7edd\u5bf9\u7684\u7a33\u59a5\u9009\u62e9\uff0c\u6211\u77e5\u9053\uff0c\u4ee3\u7cd6\u6709\u95ee\u9898\u7684\u8bba\u6587\u6211\u770b\u7684\u5f88\u591a\uff0c\u4f46\u76f4\u63a5\u5c31\u6b64\u5f52\u7eb3\u51fa\u4e00\u4e2a\u5b83\u4e0d\u5b89\u5168\uff0c\u8fd9\u4e0d\u5bf9\u554a\u3002<\/span><\/section>\n
\u8fd9\u79d1\u5b66\u5bb6\u9700\u8981\u7814\u7a76\u51e0\u5e74\u51e0\u5341\u5e74\u7684\u8def\u7a0b\uff0c\u4e0d\u80fd\u6211\u4eec\u4e00\u5f20\u5634\uff0c\u5c31\u5230\u4e86\u3002<\/span><\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n
\n
\u751a\u81f3\u6709\u4e9b\u8bba\u8c03\u662f\u8ba9\u6211\u771f\u7684\u89c9\u5f97\u8ff7\u60d1\u4e86\u3002<\/span>\u6bd4\u5982\uff0c\u4ec0\u4e48\u4f60\u559d\u65e0\u7cd6\u996e\u6599\u4e5f\u4f1a\u80d6\uff0c\u56e0\u4e3a\u8fd9\u73a9\u610f\u6709\u751c\u5473\uff0c\u8bf1\u5bfc\u7740\u4f60\u7684\u5927\u8111\u5206\u6ccc\u80f0\u5c9b\u7d20\uff0c\u8ba9\u4f60\u6d88<\/span>\u5316\u4e86\u66f4\u591a\u78b3\u6c34\uff0c\u6240\u4ee5\u66f4\u80d6\u4e86\u3002<\/span><\/section>\n
\u5927\u54e5\uff0c\u8fd9\u6211\u662f\u771f\u50bb\u4e86\u3002<\/span>\u9996\u5148\uff0c\u4f60\u559d\u7684\u65e0\u7cd6\u996e\u6599\uff0c\u5230\u5e95\u662f\u65e0\u751c\u5473\u996e\u6599\uff0c\u8fd8\u662f\u4ee3\u7cd6\u996e\u6599\uff0c\u8fd8\u662f\u65e0\u8517\u7cd6\u996e\u6599\uff1f<\/span><\/span>\u4f60\u559d\u4e00\u4e2a\u6ca1\u6709\u8517\u7cd6\u4f46\u662f\u6709\u4e73\u7cd6\u7684\u4ea7\u54c1\uff0c\u6700\u540e\u53d1\u80d6\u4e86\uff0c\u662f\u7cd6\u7684\u95ee\u9898\u8fd8\u662f\u4ee3\u7cd6\u7684\u9505\uff1f<\/span>\u4f60\u98df\u6b32\u5927\u5f00\uff0c\u591a\u5403\u4e86\u534a\u76c6\u7c73\u996d\uff0c\u90a3\u5230\u5e95\u662f\u4ee3\u7cd6\u8ba9\u4f60\u80d6\uff0c\u8fd8\u662f\u78b3\u6c34\u8ba9\u4f60\u80d6\uff1f<\/span>\u4ee3\u7cd6\u4e0d\u7edd\u5bf9\u5b89\u5168\uff0c\u4f46\u56e0\u4e3a\u7cd6\u9020\u4e86\u5b7d\uff0c\u67aa\u6bd9\u4e86\u4ee3\u7cd6\uff0c\u8fd9\u591a\u5c11\u6709\u70b9\u8ba9\u6211\u8ff7\u60d1\u3002<\/span><\/section>\n
\u56f4\u7ed5\u7740\u4e3b\u6d41\u89c2\u70b9\uff0c\u6211\u67e5\u4e86\u4e00\u4e9b\u6587\u732e\uff0c\u4ee5\u6bd4\u8f83\u5e38\u7528\u7684\u4e09\u6c2f\u8517\u7cd6\u4e3a\u4f8b\u5427\u3002<\/span><\/section>\n<\/section>\n
\n
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\u968f\u540e\u66f4\u523a\u6fc0\u7684\u6587\u732e\uff0c\u5982sasaki\u7814\u7a76\u53d1\u73b0\uff0c\u4e09\u6c2f\u8517\u7cd6200mg\u6bcf\u516c\u65a4\u4f53\u91cd\u5582\u517b\u5927\u9f20\uff0c\u80fd\u9020\u6210\u5927\u9f20\u80a0\u80c3\u548c\u80ba\u90e8\u7684DNA\u4ea7\u751f\u635f\u4f24\u3002<\/span><\/section>\n
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\u53e6\u5916\uff0c\u4efb\u4f55\u4e1c\u897f\uff0c\u629b\u5f00\u5242\u91cf\u8c08\u6bd2\u6027\uff0c\u5c31\u662f\u800d\u6d41\u6c13\u3002<\/span>\u559d\u6c34\u8fc7\u591a\u8fd8\u80fd\u76f4\u63a5\u559d\u6b7b\u4f60\u5462\u3002<\/span>\u4e00\u7b97\u5242\u91cf\u95ee\u9898\uff0c\u6211\u751a\u81f3\u60f3\u7b11\u3002<\/span><\/section>\n
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\u5927\u54e5\uff0c\u6211\u6bcf\u5929\u90fd\u80fd\u559d\u4e0a\u5feb\u4e00\u5428\u6c34\u4e86\uff0c\u80ba\u53f6\u5b50\u90fd\u80fd\u559d\u6f02\u8d77\u6765\u4e86\uff0c\u6211\u4f1a\u5728\u4e4e\u4ee3\u7cd6\u6709\u6ca1\u6709\u95ee\u9898\u5417\uff1f<\/span>\u6211\u5148\u8003\u8651\u8003\u8651\u7684\u662f\u57fa\u56e0\u9501\u7684\u95ee\u9898\uff0c\u6211\u90fd\u5f97\u63a8\u63a8\u773c\u955c\u611f\u6168\u4e00\u53e5\u51e1\u4eba\u7684\u667a\u6167\u554a\u3002<\/span><\/p>\n

03<\/span><\/strong><\/p>\n<\/section>\n

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\u4ee5\u8fd9\u4e2a\u601d\u8def\u53cd\u63a8\u3002<\/span>\u73b0\u5728\u6709\u8bb8\u591a\u8bba\u8c03\u544a\u8bc9\u6211\uff0c\u4ee3\u7cd6\u4e0d\u5b89\u5168\uff0c\u4ee3\u7cd6\u4e0d\u597d\u3002<\/span><\/section>\n
\u4e14\u4e0d\u8bba\u4e00\u4e2a\u8352\u8bde\u7684\u7ed3\u8bba\uff0c\u4e00\u5806\u65e0\u6cd5\u5b9e\u9524\u7684\u8bba\u636e\uff0c\u7a76\u7adf\u662f\u600e\u4e48\u8425\u9020\u51fa\u4ee3\u7cd6\u4e0d\u5b89\u5168\u7684\u7ed3\u8bba\uff1b<\/span>\u662f\u4e0d\u662f\u8981\u6697\u793a\u6211\uff0c\u4f60\u559d\u4ee3\u7cd6\u5c31\u662f\u5047\u81ea\u5f8b\uff0c\u5c41\u7528\u6ca1\u6709\uff0c\u60f3\u559d\u751c\u7684\uff0c\u8fd8\u662f\u5f97\u559d\u542b\u7cd6\u996e\u6599\u3002<\/span><\/section>\n
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\u79d1\u5b66\u5bb6\u5934\u90fd\u71ac\u79c3\u4e86\uff0c\u5c31\u4e3a\u4e86\u8ba9\u4f60\u653e\u5fc3\u5403\u53e3\u751c\u7684\uff0c\u4f60\u5bf9\u5f97\u8d77\u4eba\u5bb6\u7684\u5934\u53d1\u5417\uff1f<\/span><\/section>\n
\u4ee3\u7cd6\u6709\u95ee\u9898\u7684\u8bba\u6587\uff0c\u832b\u832b\u591a\u3002<\/span>\u4f46\u7cd6\u6709\u95ee\u9898\u7684\u8bba\u6587\uff0c\u66f4\u591a\u3002<\/span>\u4e0d\u63d0\u4e0e\u5b66\u672f\u7528\u8bcd\u91cd\u590d\u7684\u95ee\u9898\uff0c\u4f46\u4ee5\u8fd9\u6587\u732e\u91cf\u6765\u770b\uff0c\u6709\u7cd6\u996e\u6599\u662f\u771f\u591f\u4e0b\u5730\u72f1\u4e86\u3002<\/span>\u597d\u5bb6\u4f19\uff0c\u6492\u65e6\u80cc\u540e\u90fd\u5f97\u7eb9\u6709\u7cd6\u996e\u6599\u7684\u540d\u3002<\/span><\/section>\n
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\u4ee3\u7cd6\u6709\u98ce\u9669\u8fd8\u662f\u6709\u5f85\u7814\u7a76\uff0c\u800c\u4e14\u8fd8\u5f97\u5206\u4e0d\u540c\u7684\u6210\u5206\uff0c\u800c\u7cd6\u6709\u98ce\u9669\u8fd9\u90fd\u662f\u5b9a\u8bba\u4e86\uff0c\u5230\u5e95\u662f\u8c01\u628a\u5965\u5229\u7ed9\u90fd\u6cfc\u524d\u8005\u88e4\u5b50\u4e0a\u7684\uff1f<\/span><\/section>\n<\/section>\n
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\u8fd9\u4e9b\u5173\u4e8e\u542b\u7cd6\u996e\u6599\u5bf9\u4eba\u4f53\u597d\u4e0d\u597d\u7684\u6587\u732e\uff0c\u6211\u5c31\u4e0d\u6328\u4e2a\u9644\u4e0a\u4e86\u3002<\/span><\/section>\n<\/section>\n
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\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u90fd\u6441\u7740\u5934\u547c\u5401\u51cf\u5c11\u7cd6\u6444\u5165\uff0c\u6bcf\u5929\u4f4e\u4e8e25g\u7cd6\uff0c\u4e09\u5c81\u4ee5\u4e0b\u5b69\u5b50\u522b\u6444\u5165\u6e38\u79bb\u7cd6\u3002<\/span><\/section>\n
\u4f46\u5927\u54e5\u4f60\u8fd9\u4e00\u74f6\u6709\u7cd6\u78b3\u9178\u996e\u6599\u7684\u7cd6\u542b\u91cf\uff0c\u5c31\u76f4\u63a5\u628a\u4eba\u4e00\u4e24\u5929\u7684\u7cd6\u6444\u5165\u91cf\u90fd\u5e72\u7a7f\u3002<\/span><\/section>\n
\u522b\u7684\u4ec0\u4e48\u679c\u6c41\uff0c\u4ec0\u4e48\u9178\u5976\u7684\u542b\u7cd6\u91cf\uff0c\u66f4\u662f\u80fd\u9ad8\u5230\u5988\u90fd\u4e0d\u8ba4\u8bc6\u3002<\/span><\/section>\n
\u4ee3\u7cd6\u53ef\u80fd\u4e0d\u5b89\u5168\u3002<\/span><\/section>\n
\u4f46\u8fd9\u4e9b\u996e\u6599\u679c\u6c41\u7b49\u6709\u7cd6\u996e\u6599\uff0c\u662f\u7279\u4e48\u771f\u8981\u547d\u554a\u3002<\/span><\/section>\n
\u5408\u7740\u8fd9\u4e9b\u5356\u6709\u7cd6\u996e\u6599\u7684\u5382\u5546\uff0c\u56fd\u7c4d\u5728\u8054\u5408\u56fd\u91cc\uff1f<\/span><\/section>\n<\/section>\n
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\u751a\u81f3\u63d0\u5230\u542b\u7cd6\u996e\u6599\u8981\u6536\u7a0e\u4e86\uff0c\u5404\u4e2a\u56fd\u5bb6\u7684\u4ece\u4e1a\u8005\u53c8\u5f00\u59cb\u75af\u72c2\u62b5\u5236\u4e86\u3002<\/span><\/section>\n<\/section>\n
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\u5927\u54e5\uff0c\u8fd9\u5c31\u6ca1\u52b2\u4e86\u3002<\/span><\/section>\n
\u5173\u4e8e\u7cd6\u5403\u591a\u4e86\u4e0d\u5065\u5eb7\u8fd9\u4e8b\uff0c\u6709\u7cd6\u996e\u54c1\u5382\u5546\u3001\u8d44\u672c\u4eec\u6bd4\u8c01\u90fd\u77e5\u9053\uff0c\u600e\u4e48\u5230\u52a0\u7cd6\u8fd9\u4e00\u6b65\u65f6\u4f60\u4eec\u53c8\u88c5\u50bb\u4e86\u5462\uff1f<\/span>\u5408\u7740\u4e0d\u5173\u4e4e\u4f60\u4eec\u7684\u996d\u7897\uff0c\u6211\u7684\u5065\u5eb7\u5c31\u4e0d\u91cd\u8981\uff1b<\/span>\u5173\u4e4e\u4f60\u4eec\u996d\u7897\u4e86\uff0c\u6211\u9760\u4ee3\u7cd6\u6765\u81ea\u5f8b\u6216\u8005\u8bf4\u9ebb\u75f9\u81ea\u5df1\uff0c\u5c31\u662f\u4e0d\u7231\u60dc\u81ea\u5df1\u4e86\uff1f<\/span><\/section>\n
\u518d\u5f80\u4e0b\u67e5\uff0c\u6211\u8fd8\u53d1\u73b0\u4e86\u4e00\u4e9b\u6709\u8da3\u7684\u8d44\u6599\uff0c\u5173\u4e8e\u7f8e\u56fd\u7cd6\u4e1a\u534f\u4f1a\u7684\u9ed1\u5386\u53f2\u3002<\/span>\u6bd4\u5982\u8bf4\u4ed6\u4eec\u5f53\u5e74\u662f\u600e\u4e48\u8d5e\u52a9\u4e86\u4e00\u4e9b\u79d1\u5b66\u7814\u7a76\uff0c\u5c06\u7cd6\u9020\u6210\u51a0\u5fc3\u75c5\u98ce\u9669\u7684\u5f71\u54cd\u6de1\u5316\u7684\u3002<\/span>\u7136\u540e\u51a4\u6789\u5230\u8102\u80aa\u5934\u4e0a\u3002<\/span><\/section>\n<\/section>\n
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\u4f46\u6211\u771f\u7684\u633a\u60f3\u8bf4\u4e00\u53e5\u3002<\/span><\/section>\n
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\u8981\u5065\u5eb7\u6211\u53ea\u559d\u6c34\uff0c\u4fe9\u6211\u90fd\u4e0d\u78b0\u3002<\/span><\/section>\n
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04<\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n
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\u30101\u3011.\u3010\u4e1c\u5174\u8bc1\u5238\u3011\u201c\u65e0\u7cd6\u201d\u7cfb\u5217\u62a5\u544a\uff08\u4e8c\uff09\uff1a\u4ee3\u7cd6\u7684\u5d1b\u8d77<\/span><\/p>\n<\/section>\n

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\u30102\u3011.Cathrina H. Edwards, Megan Rossi, Christopher P. Corpe, Peter J. Butterworth, Peter R. Ellis, The role of sugars and sweeteners in food, diet and health: Alternatives for the future,Trends in Food Science & Technology,Volume 56,2016,Pages 158-166, ISSN 0924-2244,<\/span><\/p>\n

\u30103\u3011.\u5f20\u4f73\u6b23\uff0c\u9002\u7528\u4ee3\u7cd6\u6216\u589e\u52a0\u60a3\u764c\u98ce\u9669\uff0c \u79d1\u6280\u65e5\u62a5\uff0c2022\u5e743\u670830\u65e5\u7b2c004\u7248\u00a0<\/span><\/p>\n

\u30104\u3011.Eloi Chazelas, Charlotte Debras, Bernard Srour, L\u00e9opold K. Fezeu, Chantal Julia, Serge Hercberg, M\u00e9lanie Deschasaux, Mathilde Touvier, Sugary Drinks, Artificially-Sweetened Beverages, and Cardiovascular Disease in the NutriNet-Sant\u00e9 Cohort, Journal of the American College of Cardiology, Volume 76, Issue 18,2020,Pages 2175-2177,ISSN 0735-1097,<\/span><\/p>\n

\u30105\u3011.\u8d75\u6dd1\u82b9, \u9c8d\u5fe0\u5251, \u848b\u946b,\u7b49. \u4eba\u5de5\u751c\u5473\u5242\u4e09\u6c2f\u8517\u7cd6\u751f\u7269\u5b89\u5168\u6027\u7684\u7814\u7a76\u8fdb\u5c55[J]. \u4e2d\u56fd\u4e34\u5e8a\u836f\u7406\u5b66\u6742\u5fd7, 2018, 34(22):3.<\/span><\/p>\n

\u30106\u3011.ABOU DONIA M B\uff0c EI MAS\uff32Y E M\uff0c ABDEL \uff32AHMAN A A\uff0c et al. Splenda alters gut microflora and increases intestinal P\uff0dglycoprotein and cytochrome P \uff0d 450 in male rats\uff3bJ\uff3d. J Toxicol Environ Health A\uff0c 2008\uff0c 71( 21) : 1415 \uff0d 1429.<\/span><\/p>\n

\u30107\u3011.SASAKI Y F\uff0c KAWAGUCHI S\uff0c KAMAYA A\uff0c et al. The comet assay with 8 mouse organs: \uff32esults with 39 currently used food additives\uff3bJ\uff3d . Mutation \uff32esearch\uff0c2002\uff0c519( 1\uff0d2) : 103\uff0d119<\/span><\/p>\n

\u30108\u3011.Dj\u00e9sia Arnone, Caroline Chabot, Anne-Charlotte Heba, Tunay K\u00f6kten,B\u00e9n\u00e9dicte Caron, Franck Hansmannel, Natacha Dreumont, Ashwin N. Ananthakrishnan, Didier Quilliot, Laurent Peyrin-Biroulet, Sugars and Gastrointestinal Health, Clinical Gastroenterology and Hepatology,2021,,ISSN 1542-3565,<\/span><\/p>\n

\u30109\u3011.Michael D. Kendig, Kyoko Hasebe, R\u00f3is\u00edn McCague, Frances Lee, Sarah-Jane Leigh, Ria Arnold, Margaret J. Morris, Adolescent exposure to a solid high-fat, high-sugar \u2018cafeteria\u2019 diet leads to more pronounced changes in metabolic measures and gut microbiome composition than liquid sugar in female rats,Appetite, Volume 172,2022,105973, ISSN 0195-6663,<\/span><\/p>\n

\u301010\u3011.World Health Organization.\u00a0(\u200e2015)\u200e.\u00a0Guideline: sugars intake for adults and children.\u00a0World Health Organization<\/span><\/p>\n

\u301011\u3011.World Health Organization. Regional Office for Europe.\u00a0(\u200e2019)\u200e.\u00a0Ending inappropriate promotion of commercially available complementary foods for infants and young children between 6 and 36 months in Europe: a discussion paper outlining the first steps in developing a nutrient profile model to drive changes to product composition and labelling and promotion practices in the WHO European Region.\u00a0World Health Organization. Regional Office for Europe.<\/span><\/p>\n

\u301012\u3011.World Health Organization. Regional Office for Europe.\u00a0(\u200e2021)\u200e.\u00a0Expert meeting on improving drinking-water consumption for decreasing the intake of sugar-sweetened beverages and reducing plastic waste: meeting report, 27-28 February 2020, Moscow, Russian Federation.\u00a0World Health Organization. Regional Office for Europe.<\/span><\/p>\n

\u301013\u3011.Sugar Industry and Coronary Heart Disease Research: A Historical Analysis of Internal Industry Documents.JAMA Internal Medicine,2016,176 (11):1680<\/span><\/p>\n

\u301014\u3011.Sugar industry sponsorship of germ-free rodent studies linking sucrose to hyperlipidemia and cancer: An historical analysis of internal documents[J]. PLoS biology, 2017, 15(11): e2003460.<\/span><\/p>\n

\u301015\u3011.\u3010\u76ca\u666e\u7d22\u3011\u6d88\u8d39\u8005\u51cf\u7cd6\u884c\u4e3a\u548c\u6001\u5ea6\u7814\u7a76<\/span><\/p>\n

\u301016\u3011.\u3010\u56fd\u91d1\u8bc1\u5238\u3011\u57fa\u7840\u5316\u5de5\u884c\u4e1a\u7814\u7a76\uff1a\u4ee3\u7cd6\uff1a\u6d88\u8d39\u5347\u7ea7\u8d8b\u52bf\u4e0b\uff0c\u4ea7\u54c1\u767e\u82b1\u9f50\u653e<\/span><\/p>\n

\u301017\u3011.\u3010\u4e1c\u5317\u8bc1\u5238\u3011C\u4e09\u5143\uff08301206\uff09\uff1a\u8d64\u85d3\u7cd6\u9187\u5168\u7403\u9738\u4e3b\uff0c0\u7cd6\u65f6\u4ee3\u9690\u5f62\u51a0\u519b<\/span><\/p>\n

\u301018\u3011.Palinthorn Nagsuwanchart, Siriruk Nakornchai, Sroisiri Thaweboon, Rudee Surarit,Mogroside, palatinose, erythritol, and xylitol differentially affect dental plaque pH in caries-active and caries-free children: An in\u00a0vitro study,Pediatric Dental Journal,Volume 31, Issue 3,2021,Pages 242-247,ISSN 0917-2394,<\/span><\/p>\n

\u301019\u3011.Riina Runnel, Kauko K. M\u00e4kinen, Sisko Honkala, Jana Olak, Pirkko-Liisa M\u00e4kinen, Rita N\u00f5mmela, Tero Vahlberg, Eino Honkala, Mare Saag, Effect of three-year consumption of erythritol, xylitol and sorbitol candies on various plaque and salivary caries-related variables,Journal of Dentistry,Volume 41, Issue 12,2013,Pages 1236-1244,ISSN 0300-5712,<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4f5c\u8005\uff1a\u534a\u4f5b\u4ed9\u4eba<\/span><\/span><\/p>\n

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